Common and rare SCN A variants may contribute

2019-04-16

Common and rare SCN10A variants may contribute to AF susceptibility [59,60]. SCN10A mutations (R14L and R1268Q) cause a loss of function of Nav1.5 current, which is expected to reduce excitability and lead to the development of the arrhythmogenic substrate responsible for BrS and AF. A common varian

br Discussion Pericardial adhesions often

2019-04-16

Discussion Pericardial adhesions often develop after open PF-3758309 surgery, rendering a percutaneous subxiphoidal pericardial approach challenging [1–5]. Such adhesions are anticipated to be less dense in the inferior wall than in the anterior wall of the LV [1]. Therefore, there may be a chan

The mean follow up period was months

2019-04-16

The mean follow-up period was 12 months. ICD discharges and ventricular tachycardia (VT) events were recorded by reviewing Holter, exercise ECG tracings, ICD interrogation reports, and clinic visit notes. Sustained VT was considered as VT with a rate of >100 beats per minute and duration of >30s or

Autophagy can be generally divided into non

2019-04-16

Autophagy can be generally divided into non-selective bulk autophagy and selective autophagy. Non-selective autophagy breaks down proteins and organelles to provide the cell with nutrients in response to starvation. Selective autophagy removes damaged and excess organelles as well as protein sphingo

Si en La virgen de los

2019-04-16

Si en La virgen de los sicarios “la vida crapulosa está derrotando hematopoietic stem cells la muerte”, y “anda toda ventiada por Medellín día y noche en su afán haciendo lo que puede, compitiendo con semejante paridera, la más atroz [y] este continuo nacer de niños y el suero oral le están sacando

Another key challenge requires special attention in improvin

2019-04-15

Another key challenge requires special attention in improving maternal health in western China. On the basis of recent estimates, China has more than 250 million so-called rural-to-urban migrants who move from the countryside to cities to seek better paid jobs. A substantial number of these people c

Como observa Drnas de Cl ment

2019-04-15

Como observa Drnas de Clèment, los estados donde se encuentran los acuíferos generalmente son renuentes alzheimer\'s disease aceptar que se trata de recursos compartidos, e intentan aprovechar el recurso de manera desmedida y en perjuicio del Estado vecino. Así, se podrían identificar al menos dos p

Time dependent changes in the level of anxiety

2019-04-15

Time-dependent changes in the level of anxiety and proportion of patients with anxiety after ICD growth hormone secretagogue are unclear. Among patients treated with ICD for the secondary prevention of sudden cardiac death, Kamphuis et al. suggested that the proportion of patients with anxiety did

br Contributors br Funding br Conflict of interest br Patien

2019-04-11

Contributors Funding Conflict of interest Patient consent Ethics approval Acknowledgment Introduction Perforation of a cardiac chamber has been reported as a relatively rare complication of pacemaker implantation; in particular, attachment of the active-fixation atrial lead to t

The congruence between BrS and ERS

2019-04-11

The congruence between BrS and ERS with respect to clinical manifestations and response to therapy lends further support to the repolarization hypothesis. Using an experimental model of ERS, Koncz et al. [30]. recently provided evidence in support of the hypothesis that, similar to the mechanism ope

Hello world!

2018-07-29