• The primary outcome was local recurrence

  2019-05-14

  

  The primary outcome was local recurrence or metastasis. The secondary outcome included functional outcome based on Musculoskeletal Tumor Society (MSTS) score. Data for the study were retrieved from hospital records, maintained oncological files, surgical files, and clinical examination at the most r

• HBV DNA levels are associated with clinically significant pa

  2019-05-14

  

  HBV DNA levels are associated with clinically significant pathological events, such as cirrhosis; therefore, changes in the serum levels of HBV DNA could determine a risk for hepatocellular carcinoma. For on-treatment follow-up, HBeAg loss/seroconversion is important during the nucleoside therapy fo

• rgd peptide The tumor microenvironment is enriched

  2019-05-14

  

  The tumor microenvironment is enriched with EMVs that are derived not only by proliferating tumor cells, but also from infiltrating macrophages and neutrophils, and support tumor cell survival, growth, invasion and metastasis. Tumor derived EMVs also have the potential to modulate surrounding stroma

• Seg n Auerbach la parataxis

  2019-05-14

  

  Según Auerbach, la parataxis es un modo primitivo y anticlásico de narrar, típico de la Edad Media, que será sustituido gradualmente por maneras más modernas y finas de describir la realidad. No obstante, en fechas recientes ha vuelto melanocortin receptor ser practicada, por ejemplo por una serie d

• The type of ventricular arrhythmia monomorphic VT or polymor

  2019-05-13

  

  The type of ventricular arrhythmia (monomorphic VT or polymorphic VT/VF) responsible for the electrical storm provides an important diagnostic clue to its pathophysiology (Fig. 1). In this review, we address the diagnosis and specific treatments according to the type of ventricular arrhythmia and th

• Introduction Atrial fibrillation AF is the most common arrhy

  2019-05-13

  

  Introduction Atrial fibrillation (AF) is the most common arrhythmia in adults and the most common cause of embolic stroke. AF affects approximately 0.8 million patients in Japan alone, and its incidence is expected to grow exponentially [1–3]. However, the electrophysiological mechanisms of the ini

• br Conclusion br Conflict of interest

  2019-05-13

  

  Conclusion Conflict of interest Introduction Future challenges and conclusion In recent decades several anticancer drugs have been approved for the management and treatment of colorectal cancer. These drugs do not represent a revolution in the treatment of CRC. However, 5-FU has continue

• MCL has a poor long term response to current

  2019-05-13

  

  MCL has a poor long-term response to current treatment strategies, for the most commonly used R-CHOP chemotherapy (rituximab, cyclophosphamide, doxorubicin, vincristine, prednisolone), the remission rate is good (75–96%) but brief in duration. Despite the study of several other chemotherapy regimens

• ARCA Additionally the selection for subcutaneous ICD implant

  2019-05-13

  

  Additionally, the selection for subcutaneous ICD implant is based on pre-implant electrographic body surface mapping. The sensing algorithm for this system depends on the surface elecrtrocardiogram (ECG) morphology, specifically the R-and T-wave amplitudes, R/T and R/P ratios, QRS duration and QT in

• We agree that this method is

  2019-05-13

  

  We agree that this method is an appropriate way to assess whether Buruli ulcer is over-represented in children, but this issue was not central to our study. We also felt that the introduction of external data, the quality of which we cannot assess and which might not be relevant to areas where Burul

• Do ponto de vista da insurg ncia

  2019-05-13

  

  Do ponto de vista da insurgência, T-5224 resposta governamental se encaixava perfeitamente à leitura política sustentada por Guzmán. O “presidente” pregava que a ação senderista explicitaria a violência estatal, constrangendo o campesinato a se levantar contra o Estado e em última análise, tomar as

• br Hybrid approach It is still not certain

  2019-05-13

  

  Hybrid approach It is still not certain whether a single or a staged approach is safer and more effective. Natale et al. [31] performed a combined closed-chest epicardial monopolar radiofrequency ablation through a transabdominal transdiaphragmatic single port and catheter-based transseptal endoc

• br Contributors br Funding br Conflict of interest br

  2019-05-10

  

  Contributors Funding Conflict of interest Patient consent Ethics approval Acknowledgment Introduction Perforation of a cardiac chamber has been reported as a relatively rare complication of pacemaker implantation; in particular, attachment of the active-fixation atrial lead to t

• br In Sanguinetti et al and Barhanin et al

  2019-05-10

  

  In 1996, Sanguinetti et al. and Barhanin et al. independently found that, when coassembled with the accessory subunit KCNE1, the KCNQ1 and KCNE1 complex could form a channel that very closely exhibited conductive and kinetic properties similar to that of cardiac IKs[14,56]. Kass and coworkers subs

• Lead fracture was observed in of leads

  2019-05-10

  

  Lead fracture was observed in 4 of 1092 leads (0.37%); verified and incomplete lead fractures were observed in three (0.27%) and one lead (0.09%), respectively. All these fractures occurred in leads implanted by the SVP method; no fractures were observed in leads implanted by the CVC method (p Disc

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