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The energy required to drive the
2021-12-08

The energy required to drive the functional process to actively maintain lens transparency is primarily derived from the metabolism of glucose. Since the lens is avascular and exists in an environment of low oxygen tension, glucose is primarily metabolized by (R)-(-)-Niguldipine hydrochloride recept
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Knowing that our strongest phenotypic differences between th
2021-12-08

Knowing that our strongest phenotypic differences between the genotypes involved feeding behavior in various contexts, we decided to examine the case of restricted feeding and food anticipatory activity. Animals faced with a restricted schedule of food availability develop a series of anticipatory b
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For the two KO models CX and CX fluorescence
2021-12-08

For the two KO models (CX30 and CX43), fluorescence recovery is almost always best fitted with a 2-component exponential (Fig. 6A and D). Statistical analysis of the parameters (Table 1) shows that in both cases the two time scales and the fraction of recovery associated with the fast intracellular
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Nano biocatalyst prepared by assembling an enzyme
2021-12-08

Nano-biocatalyst, prepared by assembling an enzyme on nanomaterial (NM) carriers is an emerging innovation in the field of nanobiotechnology. Some of the advantages of using NM as supports in Biocytin to conventional porous supports are effective enzyme loading due to large surface area with reduce
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However Gingrich and Hen reported that absence of the gene
2021-12-08

However, Gingrich and Hen reported that absence of the gene at all stages of ontogenesis of mice may interfere with the normal developmental program and/or the organism may undergo changes in other systems to compensate for gene absence (46). In addition, potentially altered maternal behavior of GPR
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SRSF is a member of Arginine
2021-12-08

SRSF4 is a member of Arginine-Serine-rich (SR) protein family, that is essential for constitutive splicing and regulates alternative splicing [14]. SR proteins include one or two RNA recognition motifs (RRM) at their amino terminus and RS domains at carboxyl terminus [[15], [16], [17], [18]]. Wherea
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Colorectal cancer CRC is the leading cause
2021-12-08

Colorectal cancer (CRC) is the leading cause of cancer deaths in Taiwan and is also a most common cancer in the world (Huang et al., 2012, Jemal et al., 2011). With early detection and treatment in the initial stage, CRC can be recognized as curable in comparison with other malignant tumors (Levin e
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As the presence of HPV specific antibodies
2021-12-07

As the presence of HPV-specific Ciclopirox ethanolamine at time of vaccination is related to antibody response to vaccination [28], we evaluated its influence on the antibody responses among HIV+ and HIV− individuals at Months 7 and 18. Despite the small numbers, we observed that HIV+ men with detec
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Freinkel first reported in the late s that maternal
2021-12-07

Freinkel first reported in the late 1960s that maternal hypertriglyceridemia benefits the fetus during starvation by increasing maternal consumption of triglyceride for ketone body synthesis giving the basis for “accelerated starvation” theory [4,5]. This maternal metabolic reprogramming during peri
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br Several reports have shown an anti
2021-12-07

Several reports have shown an anti-proliferative effect of type I IFNs on CD4+ T 2-APB activated in vitro either upon anti-CD3 antibody treatment [28,29] or upon cognate antigen stimulation [29]. However, the in vivo setting is a lot more complex, since the final outcome is the net effect of type
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As GLO is the major detoxification system of reactive dicarb
2021-12-07

As GLO1 is the major detoxification system of reactive dicarbonyls, it is plausible that differences in production and activity of the enzyme influences AGE production and the development and/or modulation of diabetic neuropathy. Glo1 exists as a copy number variant (CNV) in many inbred strains mice
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br Perspectives br Contributors BP study concept design
2021-12-07

Perspectives Contributors BP: study concept & design, literature review, data analysis & synthesis & presentation, primary draft of the manuscript; JDR: data analysis, Fig. 1 illustration, manuscript review & revision; ZP: study concept & design, manuscript review & edit; MI: manuscript review
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Our results indicate that abcb is
2021-12-07

Our results indicate that abcb5 is likely to be a XT in zebrafish ionocytes, although, like renal cells, the phenotypes observed likely arise from the action of multiple transporters. Zebrafish lack an abcb1 ortholog, and abcb4 and abcb5 have been identified as the P-glycoproteins in zebrafish (Fis
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Acarbose and voglibose the classic glucosidase inhibitors we
2021-12-07

Acarbose and voglibose, the classic α-glucosidase inhibitors, were clinically used to inhibit α-glucosidase activity for the treatment of type 2 diabetes. However, the intake of these drugs may cause some undesirable gastrointestinal side effects and weight gain (Xu et al., 2015). The synthetic drug
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To support maximal growth and metabolic function of major
2021-12-07

To support maximal growth and metabolic function of major organs, glucose and vx680 are essential. We assessed the plasma levels of glucose and amino acids in LBW and NBW piglets at birth and at day 7 postpartum. Blood glucose levels were influenced by birthweight and age. In this study, the levels
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