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The HIF complex was initially identified as an important com
2022-08-26
The HIF complex was initially identified as an important component of the cell machinery involved in the response and potassium channel blocker to hypoxia (Semenza, 2001). Further studies have shown that HIF can also modulate whole-body energy homeostasis by controlling hypothalamic neurons (Varela
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br Conclusion br Conflict of interest Please refer to the
2022-08-26
Conclusion Conflict of interest Please refer to the accompanying ICMJE disclosure forms for further details. Exotic species such as hedgehogs are becoming popular companion animals. Therefore, they are more commonly seen in veterinary clinics. Acariasis is fairly common in these animals, us
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br Introduction Coat colors are determined by
2022-08-26
Introduction Coat colors are determined by both genetics and environment, especially genetics. The phenotype of coat color of animals depends on two types of melanin, black to brown eumelanin and yellow to reddish brown pheomelanin produced in mammalian melanocyte (Ito et al., 2000; Ito and Wakam
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GPR belongs to the G protein
2022-08-26
GPR84 belongs to the G protein-coupled receptor family, and it was first identified from human peripheral blood neutrophils [,]. GPR84 is now considered to be a member of receptor for medium chain fatty Etoricoxib (MCFA) with carbon chain lengths of 9–14 []. GPR84 is mainly expressed in bone marrow
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GLP is an intestinal peptide hormone that
2022-08-26
GLP-1 is an intestinal peptide hormone that is released by the gut following ingestion of food, particularly Sumatriptan and fats. Following its release, GLP-1 stimulates pancreatic β-cells to secrete insulin (Hirasawa et al., 2005, Covington et al., 2006). Originally, GLP-1 acted in a similar mann
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In the present study recipient oestradiol
2022-08-26
In the present study, recipient oestradiol serum levels on the day of donor oocyte retrieval or warming were found to be significantly higher in the antagonist group and higher than 100 pg/ml in all cases. Serum oestradiol level has been reported to have no effect on endometrial receptiveness in ooc
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Because HIV does not infect neurons the neurotoxicity
2022-08-26
Because HIV does not infect neurons, the neurotoxicity in HAND is thought to result from the neuroinflammation evoked by the release of viral proteins and cytokines from infected microglia and macrophages (Ellis et al., 2007; Saylor et al., 2016). Viral tropism is determined by gp120 binding to CD4
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Oxidative stress results from the disequilibrium
2022-08-26
Oxidative stress results from the disequilibrium between levels of prooxidant molecules produced and the ability of a biological system to detoxify and neutralize the reactive molecules [14]. OS is a chronic, self-perpetuating state of damage to cells and increased inflammation resulting from the co
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We compared the age BMI and relevant laboratory variables
2022-08-26
We compared the age, BMI and relevant laboratory variables between the two groups of risk factor multiplicity. The results are presented in Table 7 for the women and in Table 8 for the men. The individuals with an increased erythrocyte adhesiveness/aggregation can clearly be seen to be older, more o
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Polyunsaturated fatty acids PUFAs represent a class of lipid
2022-08-26
Polyunsaturated fatty acids (PUFAs) represent a class of lipids that contain two or more carbon double (unsaturated) bonds (CC) and classified as n-3, n-6 and n-9 fatty acids. PUFAs including n-3 such as docosahexaenoic aurora a mg (DHA), eicosapentaenoic acid (EPA) and n-6 such as arachidonic acid
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BDNF is intricately implicated in
2022-08-25
BDNF is intricately implicated in energy homeostasis (Hamdouchi et al., 2016; Schwartz and Mobbs, 2012), regulation of mood (Sartorius et al., 2015) and adult neurogenesis (Taliaz et al., 2010; Waterhouse et al., 2012), our primary focus was to evaluate the effects of GPR40 stimulation on BDNF expre
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L 012 sodium salt Considering the fact that NADPH oxidase is
2022-08-25
Considering the fact that NADPH oxidase is the main source for paraquat and maneb-induced oxidative stress, we hypothesized that NADPH oxidase activation might contribute to dopaminergic neurodegeneration induced by paraquat and maneb through ferroptosis. To test our hypothesis, we investigated the
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Results of studies on fish FBPase
2022-08-25
Results of studies on fish FBPase are somewhat confusing: although fishes skeletal muscles possess relatively high FBPase activity (Knox et al., 1980, Lushchak et al., 2001) and the isozyme present therein has kinetic properties typical to all vertebrates muscle FBPases (Rosenmann et al., 1977), inv
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Although oxidative stress induces a decrease in
2022-08-24
Although oxidative stress induces a decrease in intracellular ATP level, the underlying mechanism is obscured. We hypothesized that oxidative stress induced by H2O2 could decrease astrocytes ATP level through lysosome exocytosis in Ca2+-dependent pattern. In present study, using H2O2 stimulation to
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It has been suggested that
2022-08-24
It has been suggested that MAPK (Huang et al., 2013, Uddman et al., 2003, Xu et al., 2008) signaling pathway is involved in the transcriptional upregulation of ETB receptor. The present study demonstrated that treatment with CsA increased phosphorylation of ERK1/2 and p38. Inhibition of ERK1/2 and p
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