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The purpose of this study is to examine the relationship
2023-08-10

The purpose of this γ-Linolenic Acid methyl ester study is to examine the relationship between ACEs and engagement in treatment among a sample of youth in residential treatment centers (RTCs). It is hypothesized that youth with higher ACE scores will have lower levels of engagement in treatment. In
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90 The anorexic effect observed when AR is infused
2023-08-10

The anorexic effect observed when AR231630 is infused into the VTA could be the result of the DA release inhibition, as previously described [11]. However, there is also a hedonic aspect in feeding that possibly involves dopaminergic mechanisms of reward. Helm et al. showed a functional link between
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Despite their different effects on cell survival
2023-06-29

Despite their different effects on cell survival, the functions of autophagy and apoptosis are not completely independent. Additionally, Cho et al. (2009) suggested that the mediation of caspase-3 links the apoptotic and autophagic signaling pathways. Consequently, to illuminate the correlation, exc
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br Methods and results ACE is a Canadian
2023-06-15

Methods and results ACE is a Canadian satellite mission [7] that measures atmospheric Thiomyristoyl australia spectra in the limb geometry using the Sun as a light source (solar occultation). The ACE orbit (74° inclination to the equator, 650 km altitude) concentrates measurements at high latitu
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br Conclusion br Conflicts of interest br Introduction
2023-06-14

Conclusion Conflicts of interest Introduction RNA interference is a specific post-transcriptional gene silencing mechanism within a cell via the transfection of microRNAs (miRNA), exogenous small interfering RNAs (siRNA) or small hairpin RNAs (shRNA) [1–3]. Transfection of shRNA can be done
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Five alternatively spliced isoforms of ATX have been
2023-06-13

Five alternatively-spliced isoforms of ATX have been described and all are catalytically active [16], [17]. The original ATX described in 1992 is termed ATXα, whereas the most abundant isoform is ATXβ and is the same isoform responsible for plasma lysoPLD activity [18]. Full length ATX is synthesize
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MafB a member of the Maf protein family is essential
2023-06-13

MafB, a member of the Maf protein family, is essential for terminal differentiation of macrophages (Kelly et al., 2000). The phagocytic activity of polystyrene beads was found to be enhanced in Ro 3306 with exogenous expression of MafB (Tillmanns et al., 2007). However, in alveolar macrophages of d
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Pompe disease is accompanied by the deficiency of the lysoso
2023-06-13

Pompe disease is accompanied by the deficiency of the lysosomal α-1,4-glucosidase that makes the c di gmp receptor unable to hydrolyze glycogen to glucose, thereby resulting in the accumulation of glycogen in lysosomes, especially in skeletal muscles and cardiac tissues. This accumulation results in
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We have recently reported a regulatory effect of
2023-06-13

We have recently reported a regulatory effect of quercetin on the AChE activity in the brainstem during the demyelination and remyelination process [17]. It has also been observed that there is a protective effect on lipid peroxidation and worsening of motor functions caused by loss of myelin in the
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In bacteria H gler et
2023-06-13

In bacteria (Hügler et al., 2007, Kanao et al., 2001), a glaucophyte alga (Ma et al., 2001), green algae/land plants (Fatland et al., 2002), and filamentous fungi (Nowrousian et al., 2000), ACL enzyme activity requires ACLA, and ACLB (referred to here as dual-subunit ACL, or dsACL) (Kanao et al., 20
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and LO are members of the lipoxygenase family that convert
2023-06-13

5- and 12/15-LO are members of the lipoxygenase family that convert arachidonic Moxifloxacin into lipid mediators such as leukotriene B4 (LTB) and 12()-hydroxyeicosatetraenoic acid (HETE) and 15()-HETE, respectively. Evidence from several in vitro and in vivo studies has shown that activation of the
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br Current limitations and future directions There are sever
2023-06-12

Current limitations and future directions There are several limitations associated with PET imaging of aromatase using carbon-11 labeled aromatase inhibitors. Due to the very short half-life of carbon 11 (20min), PET studies with currently available, validated tracers can only be performed in med
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Reactive oxygen species is an aspect of
2023-06-08

Reactive oxygen species is an aspect of oxidative stress which are associated with many diseases such as rheumatoid arthritis, diabetes, inflammation, atherosclerosis and cancers (Collins, 2005; Halliwell, 1994). Thus, the need for naturally occurring antioxidants is of crucial importance. Some biop
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Adenosine is an endogenous nucleoside that plays pivotal rol
2023-06-01

Adenosine is an endogenous nucleoside that plays pivotal roles in different physiological and pathophysiological processes by triggering specific cell-surface receptors both in the SB 216763 and in the periphery. The adenosine receptors (ARs) are four different subtypes of G protein-coupled receptor
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Children with ADA SCID commonly suffer from a variety
2023-05-31

Children with ADA-SCID commonly suffer from a variety of opportunistic infections, including viral, fungal, and mycobacterial infections. Due to defects in n acetylneuraminic acid mg and IG production, they are also susceptible to infection with encapsulated bacteria such as Haemophilus influenzae,
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